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Drosophila seminal fluid has the property of reducing the female's interest in remating, increasing her rate of egg-laying, and is also mildly toxic. Artificial selection in the lab can produce females that are resistant to the effects, and males that produce more and more potent semen to overcome their resistance, to the point where the line of "super potent" males, when crossed to unselected females, kill their partners with their ejaculations. There is literally a battle of the sexes in these species.Rice WR (1996) Sexually antagonistic male adaptation triggered by experimental arrest of female evolution. Nature 381(6579):189-90.